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    September 25

    Comparison of Lymphoctes involved in the Immune response.

    Comparison of Lymphoctes involved in the Immune response.

    Property

    T Cells

    B Cells

    Origin

    Bone Marrow

    Bone Marrow

    Maturation and expression of antigen receptor

    Thymus

    Bone Marrow; Bursa of Fabricius in bird

    Differentiation

    Lymphoid tissue

    Lymphoid tissue

    Mobility

    Great

    Very little (some stage circulate)

    Complement receptors

    Absent

    Present

    Surface immunoglobulins

    Absent

    Present

    Proliferation

    Upon antigenic stimulation, profilerate and differentiate into effector and memory cells

    Upon antigenic stimulation, profilerate and differentiate into plasma and memory cells

    Immunity Types

    Cell mediated and humoral immunity (B cells activation by TH cells)

    Humoral

    Distribution

    High in blood, lymph, and lymphoid tissue

    High in spleen, lymph nodes, bone marrow and other lymphoid tissue; low in blood

    Secretory protein

    Cytokines

    Antibodies

    Subsets and functions

    T-Helper cell: necessary for B-cell antivation by T-depedent antigens and T-effector cells. There are three types of T-helper cell TH1, TH2 and TH0

    Cytotoxic T cell: Differentiates into a CTL that lyses cells recognized as nonself and virus or parasite infected cells.

    Memory cells: a long-lived cell responsible for the anmnestic response

    Memory Cell : a long-lived cell responsible for the anamnestic response.

     

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