Property

T Cells

B Cells

Origin

Bone Marrow

Bone Marrow

Maturation and expression of antigen receptor

Thymus

Bone Marrow; Bursa of Fabricius in bird

Differentiation

Lymphoid tissue

Lymphoid tissue

Mobility

Great

Very little (some stage circulate)

Complement receptors

Absent

Present

Surface immunoglobulins

Absent

Present

Proliferation

Upon antigenic stimulation, profilerate and differentiate into effector and memory cells

Upon antigenic stimulation, profilerate and differentiate into plasma and memory cells

Immunity Types

Cell mediated and humoral immunity (B cells activation by TH cells)

Humoral

Distribution

High in blood, lymph, and lymphoid tissue

High in spleen, lymph nodes, bone marrow and other lymphoid tissue; low in blood

Secretory protein

Cytokines

Antibodies

Subsets and functions

T-Helper cell: necessary for B-cell antivation by T-depedent antigens and T-effector cells. There are three types of T-helper cell TH1, TH2 and TH0

Cytotoxic T cell: Differentiates into a CTL that lyses cells recognized as nonself and virus or parasite infected cells.

Memory cells: a long-lived cell responsible for the anmnestic response

Memory Cell : a long-lived cell responsible for the anamnestic response.